免疫原
Synthesized peptide derived from human N-ternal ADX
特异性
This antibody detects endogenous levels of ADX at Human, Mouse,Rat
组成(Formulation)
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
稀释比例
WB 1:500-2000 IHC 1:50-200
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
功能
Essential for the synthesis of various steroid hormones . Participates in the reduction of mitochondrial cytochrome P450 for steroidogenesis . Transfers electrons from adrenodoxin reductase to CYP11A1, a cytochrome P450 that catalyzes cholesterol side-chain cleavage . Does not form a ternary complex with adrenodoxin reductase and CYP11A1 but shuttles between the two enzymes to transfer electrons (By similarity).
蛋白名称
Adrenodoxin, mitochondrial (Adrenal ferredoxin) (Ferredoxin-1) (Hepatoredoxin)
其他名称
Adrenodoxin, mitochondrial (Adrenal ferredoxin) (Ferredoxin-1) (Hepatoredoxin)
细胞定位
Mitochondrion matrix .
组织表达
Highest levels in the adrenal gland (at protein level). Also detected in kidney and testis (at protein level).