免疫原
Synthesized peptide derived from human C-ternal PANX1
特异性
This antibody detects endogenous levels of PANX1 at Human, Mouse,Rat
组成(Formulation)
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
稀释比例
WB 1:500-2000 IHC 1:50-200
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
功能
Structural component of the gap junctions and the hemichannels involved in the ATP release and nucleotide permeation . May play a role as a Ca(2+)-leak channel to regulate ER Ca(2+) homeostasis . Plays a critical role in oogenesis .
基因名称(Gene Name)
PANX1 MRS1 UNQ2529/PRO6028
细胞定位
Cell membrane ; Multi-pass membrane protein . Cell junction, gap junction . Endoplasmic reticulum membrane ; Multi-pass membrane protein .
组织表达
Widely expressed (PubMed:30918116). Highest expression is observed in oocytes and brain (PubMed:30918116). Detected at very low levels in sperm cells (PubMed:30918116).