免疫原
Synthesized peptide derived from human N-ternal SIPA1
特异性
This antibody detects endogenous levels of SIPA1 at Human, Mouse
组成（Formulation）
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
稀释比例
WB 1:500-2000 IHC 1:50-200
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
功能
GTPase activator for the nuclear Ras-related regulatory proteins Rap1 and Rap2 in vitro, converting them to the putatively inactive GDP-bound state . Affects cell cycle progression (By similarity).
基因名称（Gene Name）
SIPA1 SPA1
蛋白名称
Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase-activating protein Spa-1) (p130 SPA-1)
其他名称
Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase-activating protein Spa-1) (p130 SPA-1)
细胞定位
Nucleus . Cytoplasm, perinuclear region . Endomembrane system; Peripheral membrane protein . Mostly localized in the perinuclear membraneous region. .
组织表达
Expressed in fetal as well as in adult tissues. Expressed abundantly in the lymphoid tissues such as thymus, spleen and peripheral blood lymphocytes and also shows a significant expression in the spinal cord.
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