免疫原
Synthesized peptide derived from human N-ternal WNT2B
特异性
This antibody detects endogenous levels of WNT2B at Human, Mouse
组成(Formulation)
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
稀释比例
WB 1:500-2000 IHC 1:50-200
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
功能
Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt/beta-catenin signaling pathway. Plays a redundant role in embryonic lung development.
基因名称(Gene Name)
WNT2B WNT13
蛋白名称
Protein Wnt-2b (Protein Wnt-13)
其他名称
Protein Wnt-2b (Protein Wnt-13)
细胞定位
Secreted, extracellular space, extracellular matrix . Secreted .
组织表达
Isoform 1 is expressed in adult heart, brain, placenta, lung, prostate, testis, ovary, small intestine and colon. In the adult brain, it is mainly found in the caudate nucleus, subthalamic nucleus and thalamus. Also detected in fetal brain, lung and kidney. Isoform 2 is expressed in fetal brain, fetal lung, fetal kidney, caudate nucleus, testis and cancer cell lines.