免疫原
Synthesized peptide derived from human C-ternal REEP5
特异性
This antibody detects endogenous levels of REEP5 at Human, Mouse,Rat
组成(Formulation)
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
稀释比例
WB 1:500-2000 IHC 1:50-200
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
功能
Plays an essential role in heart function and development by regulating the organization and function of the sarcoplasmic reticulum in cardiomyocytes.
基因名称(Gene Name)
REEP5 C5orf18 DP1 TB2
蛋白名称
Receptor expression-enhancing protein 5 (Polyposis locus protein 1) (Protein TB2)
其他名称
Receptor expression-enhancing protein 5 (Polyposis locus protein 1) (Protein TB2)
细胞定位
Endoplasmic reticulum membrane ; Multi-pass membrane protein . Sarcoplasmic reticulum membrane ; Multi-pass membrane protein . Localizes to endoplasmic reticulum tubular network (PubMed:23969831). In cardiomyocytes, localizes to the junctional sarcoplasmic reticulum membrane which is closely tethered to the cell membrane and contractile machinery (By similarity). .
组织表达
Expressed in heart (at protein level) (PubMed:32075961). Expressed in circumvallate papillae and testis (PubMed:16720576).