免疫原
The antiserum was produced against synthesized peptide derived from human NT. AA range:235-284
特异性
Neurotrimin Polyclonal Antibody detects endogenous levels of Neurotrimin protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/20000.. IF 1:50-200
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
This gene encodes a member of the IgLON (LAMP, OBCAM, Ntm) family of immunoglobulin (Ig) domain-containing glycosylphosphatidylinositol (GPI)-anchored cell adhesion molecules. The encoded protein may promote neurite outgrowth and adhesion via a homophilic mechanism. This gene is closely linked to a related family member, opioid binding protein/cell adhesion molecule-like (OPCML), on chromosome 11. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2009],
功能
function:Neural cell adhesion molecule.,similarity:Belongs to the immunoglobulin superfamily. IgLON family.,similarity:Contains 3 Ig-like C2-type (immunoglobulin-like) domains.,
其他名称
NTM; IGLON2; NT; Neurotrimin; hNT; IgLON family member 2
细胞定位
Cell membrane; Lipid-anchor, GPI-anchor.