免疫原
The antiserum was produced against synthesized peptide derived from human GJB7. AA range:21-70
特异性
Connexin 25 Polyclonal Antibody detects endogenous levels of Connexin 25 protein.
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
Connexins, such as GJB7, are involved in the formation of gap junctions, intercellular conduits that directly connect the cytoplasms of contacting cells. Each gap junction channel is formed by docking of 2 hemichannels, each of which contains 6 connexin subunits (Sohl et al., 2003 [PubMed 12881038]).[supplied by OMIM, Mar 2008],
功能
function:One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.,similarity:Belongs to the connexin family. Beta-type (group I) subfamily.,subunit:A connexon is composed of a hexamer of connexins.,tissue specificity:Weakly expressed in placenta.,
蛋白名称
Gap junction beta-7 protein
其他名称
GJB7; CX25; Gap junction beta-7 protein; Connexin-25; Cx25
细胞定位
Cell membrane ; Multi-pass membrane protein . Cell junction, gap junction .
组织表达
Weakly expressed in placenta.
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