免疫原
The antiserum was produced against synthesized peptide derived from human CDON. AA range:511-560
特异性
CDO Polyclonal Antibody detects endogenous levels of CDO protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
This gene encodes a cell surface receptor that is a member of the immunoglobulin superfamily. The encoded protein contains three fibronectin type III domains and five immunoglobulin-like C2-type domains. This protein is a member of a cell-surface receptor complex that mediates cell-cell interactions between muscle precursor cells and positively regulates myogenesis. [provided by RefSeq, Aug 2011],
功能
function:Component of a cell-surface receptor complex that mediates cell-cell interactions between muscle precursor cells. Promotes differentiation of myogenic cells.,PTM:N-glycosylated.,similarity:Contains 3 fibronectin type-III domains.,similarity:Contains 5 Ig-like C2-type (immunoglobulin-like) domains.,subunit:Part of a complex that contains BOC, CDON, NEO1, cadherins and CTNNB1. Interacts with NTN3.,
蛋白名称
Cell adhesion molecule-related/down-regulated by oncogenes
其他名称
CDON; CDO; Cell adhesion molecule-related/down-regulated by oncogenes
Fields
>>Hedgehog signaling pathway
细胞定位
Cell membrane ; Single-pass membrane protein .
组织表达
Fetal brain,Fetal lung,Placenta,