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SYK Monoclonal Antibody

说明书

BYab-16307

  • 20UL ¥460 50UL ¥945 100UL ¥1350
  • 货期: 3天左右

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宿主
反应性
应用
WB;ELISA
分子量(DA)
免疫原
Purified recombinant fragment of SYK (aa296-484) expressed in E. Coli.
特异性
SYK Monoclonal Antibody detects endogenous levels of SYK protein.
来源
Monoclonal, Mouse
组成(Formulation)
Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.
稀释比例
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
纯化工艺(Immunogen)
Affinity purification
浓度
背景(Background)
Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. Two transcript variants encoding two different isoforms have been found for this gene, but only the longer variant encodes a functional transporter. [provided by RefSeq, Jul 2008],
功能
caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,function:Translocates a broad array of organic cations with various structures and molecular weights including the model compounds 1-methyl-4-phenylpyridinium (MPP), tetraethylammonium (TEA), N-1-methylnicotinamide (NMN), 4-(4-(dimethylamino)styryl)-N-methylpyridinium (ASP), the endogenous compounds choline, guanidine, histamine, epinephrine, adrenaline, noradrenaline and dopamine, and the drugs quinine, and metformin. The transport of organic cations is inhibited by a broad array of compounds like tetramethylammonium (TMA), cocaine, lidocaine, NMDA receptor antagonists, atropine, prazosin, cimetidine, TEA and NMN, guanidine, cimetidine, choline, procainamide, quinine, tetrabutylammonium, and tetrapentylammonium. Translocates organic cations in an electroge
基因名称(Gene Name)
SLC22A1
蛋白名称
Solute carrier family 22 member 1
简称
SYK
其他名称
SLC22A1; OCT1; Solute carrier family 22 member 1; Organic cation transporter 1; hOCT1
Fields
>>Bile secretion;>>Choline metabolism in cancer
人基因ID
6580
人蛋白质序列数据库
O15245
小鼠基因ID
小鼠蛋白质序列数据库
O08966
大鼠基因ID
大鼠蛋白质序列数据库
细胞定位
Basolateral cell membrane ; Multi-pass membrane protein .
组织表达
Widely expressed with high level in liver. Isoform 1 and isoform 2 are expressed in liver. Isoform 1, isoform 2, isoform 3 and isoform 4 are expressed in glial cell lines.
储存(Storage)
-20°C/1 year

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SYK Monoclonal Antibody

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