免疫原
The antiserum was produced against synthesized peptide derived from human RAB5C. AA range:122-171
特异性
Rab 5C Polyclonal Antibody detects endogenous levels of Rab 5C protein.
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/5000.. IF 1:50-200
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
Members of the Rab protein family are small GTPases of the Ras superfamily that are thought to ensure fidelity in the process of docking and/or fusion of vesicles with their correct acceptor compartment (Han et al., 1996 [PubMed 8646882]).[supplied by OMIM, Nov 2010],
功能
function:Protein transport. Probably involved in vesicular traffic.,similarity:Belongs to the small GTPase superfamily. Rab family.,subcellular location:Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,subunit:Binds EEA1.,
蛋白名称
Ras-related protein Rab-5C
其他名称
RAB5C; RABL; Ras-related protein Rab-5C; L1880; RAB5L
Fields
>>Ras signaling pathway;>>Endocytosis;>>Phagosome;>>Vasopressin-regulated water reabsorption;>>Salmonella infection;>>Amoebiasis;>>Tuberculosis
细胞定位
Cell membrane ; Lipid-anchor ; Cytoplasmic side . Early endosome membrane ; Lipid-anchor . Melanosome . Identified by mass spectrometry in melanosome fractions from stage I to stage IV. .
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