免疫原
The antiserum was produced against synthesized peptide derived from human RAB11B. AA range:164-213
特异性
Rab 11B Polyclonal Antibody detects endogenous levels of Rab 11B protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB 1:500-2000;IHC-p 1:50-300
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
The Ras superfamily of small GTP-binding proteins, which includes the Ras (see MIM 190020), Ral (see MIM 179550), Rho (see MIM 165390), Rap (see MIM 179520), and Rab (see MIM 179508) families, is involved in controlling a diverse set of essential cellular functions. The Rab family, including RAB11B, appears to play a critical role in regulating exocytotic and endocytotic pathways (summary by Zhu et al., 1994 [PubMed 7811277]).[supplied by OMIM, Nov 2010],
功能
function:Possesses GTPase activity.,similarity:Belongs to the small GTPase superfamily. Rab family.,subunit:Interacts with RAB11FIP1, RAB11FIP2, RAB11FIP3 and RAB11FIP4.,
蛋白名称
Ras-related protein Rab-11B
其他名称
RAB11B; YPT3; Ras-related protein Rab-11B; GTP-binding protein YPT3
Fields
>>Endocytosis;>>AMPK signaling pathway;>>Vasopressin-regulated water reabsorption;>>Influenza A
细胞定位
Recycling endosome membrane ; Lipid-anchor ; Cytoplasmic side . Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane ; Lipid-anchor ; Cytoplasmic side . Cytoplasmic vesicle, phagosome membrane ; Lipid-anchor ; Cytoplasmic side . Recruited to phagosomes containing S.aureus. .
组织表达
B-cell lymphoma,Brain,Cerebellum,Muscle,