免疫原
The antiserum was produced against synthesized peptide derived from human GTPBP5. AA range:71-120
特异性
GTPBP5 Polyclonal Antibody detects endogenous levels of GTPBP5 protein.
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
IHC: 1/100 - 1/300. ELISA: 1/20000.. IF 1:50-200
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
Small G proteins, such as GTPBP5, act as molecular switches that play crucial roles in the regulation of fundamental cellular processes such as protein synthesis, nuclear transport, membrane trafficking, and signal transduction (Hirano et al., 2006 [PubMed 17054726]).[supplied by OMIM, Mar 2008],
功能
function:Involved in the ribosome maturation process. Plays a role of GTPase in vitro. When missing, mitochondria elongation and abnormal nuclear morphology are observed.,sequence caution:Translated as Gln.,similarity:Belongs to the GTP1/OBG family.,
蛋白名称
GTP-binding protein 5
其他名称
GTPBP5; OBGH1; GTP-binding protein 5; Protein obg homolog 1; ObgH1
细胞定位
Mitochondrion. Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
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