免疫原
The antiserum was produced against synthesized peptide derived from human GTPBP2. AA range:31-80
特异性
GTPBP2 Polyclonal Antibody detects endogenous levels of GTPBP2 protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
GTP-binding proteins, or G proteins, constitute a superfamily capable of binding GTP or GDP. G proteins are activated by binding GTP and are inactivated by hydrolyzing GTP to GDP. This general mechanism enables G proteins to perform a wide range of biologic activities.[supplied by OMIM, Jan 2003],
功能
induction:Up-regulated by IFN-gamma in human monocytic cell line THP-1.,similarity:Belongs to the GTPBP1 GTP-binding protein family.,tissue specificity:Predominantly expressed in thymus, spleen, and testis. Expressed at lower levels in brain, lung, kidney, and ovary.,
蛋白名称
GTP-binding protein 2
其他名称
GTPBP2; GTP-binding protein 2
细胞定位
intracellular,intracellular membrane-bounded organelle,
组织表达
Predominantly expressed in thymus, spleen, and testis. Expressed at lower levels in brain, lung, kidney, and ovary.