免疫原
The antiserum was produced against synthesized peptide derived from human GBP3. AA range:481-530
特异性
GBP3 Polyclonal Antibody detects endogenous levels of GBP3 protein.
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/10000.. IF 1:50-200
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
This gene encodes a member of the guanylate-binding protein (GBP) family. GBPs specifically bind guanine nucleotides (GMP, GDP, and GTP) and contain two of the three consensus motifs found in typical GTP-binding proteins. The encoded protein interacts with a member of the germinal center kinase family. Multiple transcript variants encoding different isoforms have been been found for this gene. [provided by RefSeq, Jan 2016],
功能
function:Binds GTP, GDP and GMP.,sequence caution:Contaminating sequence. Potential poly-A sequence.,sequence caution:Unlikely isoform. Aberrant splice sites.,similarity:Belongs to the GBP family.,
蛋白名称
Guanylate-binding protein 3
其他名称
GBP3; Guanylate-binding protein 3; GTP-binding protein 3; GBP-3; Guanine nucleotide-binding protein 3
Fields
>>NOD-like receptor signaling pathway
细胞定位
Cytoplasm . Cytoplasm, perinuclear region . Golgi apparatus membrane . Heterodimers with GBP1, GBP2 and GBP5 localize in the compartment of the prenylated GBPs: with GBP1 in a vesicle-like compartment, with GBP2, around the nucleus and with GBP-5, at the Golgi apparatus. .
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