免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human BMP6. AA range:341-390
特异性
BMP-6 Polyclonal Antibody detects endogenous levels of BMP-6 protein.
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates a wide range of biological processes including iron homeostasis, fat and bone development, and ovulation. Differential expression of this gene may be associated with progression of breast and prostate cancer. Mutations in this gene may be associated with iron overload in human patients. [provided by RefSeq, Jul 2016],
功能
function:Induces cartilage and bone formation.,online information:Bone morphogenetic protein 6 entry,similarity:Belongs to the TGF-beta family.,subunit:Interacts with SOSTDC1.,
蛋白名称
Bone morphogenetic protein 6
其他名称
BMP6; VGR; Bone morphogenetic protein 6; BMP-6; VG-1-related protein; VG-1-R; VGR-1
Fields
>>Cytokine-cytokine receptor interaction;>>TGF-beta signaling pathway;>>Hippo signaling pathway;>>Ovarian steroidogenesis
组织表达
Bone,PCR rescued clones,
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