免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human XCL1/XCL2. AA range:51-100
特异性
Lymphotactin Polyclonal Antibody detects endogenous levels of Lymphotactin protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000.. IF 1:50-200
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
This antimicrobial gene encodes a member of the chemokine superfamily. Chemokines function in inflammatory and immunological responses, inducing leukocyte migration and activation. The encoded protein is a member of the C-chemokine subfamily, retaining only two of four cysteines conserved in other chemokines, and is thought to be specifically chemotactic for T cells. This gene and a closely related family member are located on the long arm of chromosome 1. [provided by RefSeq, Sep 2014],
功能
function:Chemotactic activity for lymphocytes but not for monocytes or neutrophils.,online information:XCL1 entry,similarity:Belongs to the intercrine gamma family.,tissue specificity:Highest level in spleen, lower in peripheral leukocytes and very low levels in lung, colon and small intestine.,
基因名称(Gene Name)
XCL1/XCL2
蛋白名称
Lymphotactin/Cytokine SCM-1 beta
其他名称
XCL1; LTN; SCYC1; Lymphotactin; ATAC; C motif chemokine 1; Cytokine SCM-1; Lymphotaxin; SCM-1-alpha; Small-inducible cytokine C1; XC chemokine ligand 1; XCL2; SCYC2; Cytokine SCM-1 beta; C motif chemokine 2; XC chemokine ligand 2
Fields
>>Cytokine-cytokine receptor interaction;>>Viral protein interaction with cytokine and cytokine receptor;>>Chemokine signaling pathway
组织表达
Highest level in spleen, lower in peripheral leukocytes and very low levels in lung, colon and small intestine.