免疫原
The antiserum was produced against synthesized peptide derived from human IL-20Ralpha. AA range:173-222
特异性
IL-20Rα Polyclonal Antibody detects endogenous levels of IL-20Rα protein.
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
This gene encodes a member of the type II cytokine receptor family. The encoded protein is a subunit of the receptor for interleukin 20, a cytokine that may be involved in epidermal function. The interleukin 20 receptor is a heterodimeric complex consisting of the encoded protein and interleukin 20 receptor beta. This gene and interleukin 20 receptor beta are highly expressed in skin, and are upregulated in psoriasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],
功能
function:The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL20RA/IL10RB dimer is a receptor for IL26.,similarity:Belongs to the type II cytokine receptor family.,similarity:Contains 2 fibronectin type-III domains.,subunit:Heterodimer with IL20RB and heterodimer with IL10RB.,tissue specificity:Widely expressed with highest levels in skin and testis and high levels in brain. Highly expressed in psoriatic skin.,
蛋白名称
Interleukin-20 receptor subunit alpha
其他名称
IL20RA; Interleukin-20 receptor subunit alpha; IL-20 receptor subunit alpha; IL-20R-alpha; IL-20RA; Cytokine receptor class-II member 8; Cytokine receptor family 2 member 8; CRF2-8; IL-20R1; ZcytoR7
Fields
>>Cytokine-cytokine receptor interaction;>>Viral protein interaction with cytokine and cytokine receptor;>>JAK-STAT signaling pathway
细胞定位
Membrane ; Single-pass type I membrane protein .
组织表达
Widely expressed with highest levels in skin and testis and high levels in brain. Highly expressed in psoriatic skin.
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