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EPO Monoclonal Antibody

说明书

BYab-15831

  • 20UL ¥460 50UL ¥945 100UL ¥1350
  • 货期: 3天左右

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宿主
反应性
应用
WB;IF;ELISA
分子量(DA)
免疫原
Purified recombinant fragment of human EPO expressed in E. Coli.
特异性
EPO Monoclonal Antibody detects endogenous levels of EPO protein.
来源
Monoclonal, Mouse
组成(Formulation)
Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.
稀释比例
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
纯化工艺(Immunogen)
Affinity purification
浓度
背景(Background)
This gene is a member of the EPO/TPO family and encodes a secreted, glycosylated cytokine composed of four alpha helical bundles. The protein is found in the plasma and regulates red cell production by promoting erythroid differentiation and initiating hemoglobin synthesis. This protein also has neuroprotective activity against a variety of potential brain injuries and antiapoptotic functions in several tissue types. [provided by RefSeq, Jul 2008],
功能
disease:Genetic variation in EPO is associated with susceptbility to microvascular complications of diabetes type 2 (MVCD2) [MIM:612623]; also called susceptibility to proliferative diabetic retinopathy (PDR) or susceptbility to diabetic end-stage renal disease (ESRD). Significant morbidity and mortality among patients with diabetes mellitus result largely from a greatly increased incidence of microvascular complications. PDR and ESRD are two of the most common and severe microvascular complications of diabetes. A high concordance exists in the development of PDR and ESRD in diabetic patients, as well as strong familial aggregation of these complications, suggesting a common underlying genetic mechanism. EPO is a potent angiogenic factor observed in the diabetic human and mouse eye.,function:Erythropoietin is the principal hormone involved in the regulation of erythrocyte differentiation
基因名称(Gene Name)
EPO
蛋白名称
Erythropoietin
简称
EPO
其他名称
EPO; Erythropoietin; Epoetin
Fields
>>Cytokine-cytokine receptor interaction;>>HIF-1 signaling pathway;>>PI3K-Akt signaling pathway;>>JAK-STAT signaling pathway;>>Hematopoietic cell lineage;>>Pathways in cancer
人基因ID
2056
人蛋白质序列数据库
P01588
小鼠基因ID
小鼠蛋白质序列数据库
P07321
大鼠基因ID
大鼠蛋白质序列数据库
细胞定位
Secreted .
组织表达
Produced by kidney or liver of adult mammals and by liver of fetal or neonatal mammals.
储存(Storage)
-20°C/1 year

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EPO Monoclonal Antibody

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