免疫原
The antiserum was produced against synthesized peptide derived from human HOXA1/B1/D1. AA range:216-265
特异性
Hox-A1/B1/D1 Polyclonal Antibody detects endogenous levels of Hox-A1/B1/D1 protein.
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
IHC: 1/100 - 1/300. ELISA: 1/10000.. IF 1:50-200
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXB genes located in a cluster on chromosome 17. [provided by RefSeq, Jul 2008],
功能
function:Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures.,polymorphism:The two common alleles; HOX1B*A and HOX1B*B have a frequency of 78.8% and 21.2% respectively.,similarity:Belongs to the Antp homeobox family. Labial subfamily.,similarity:Contains 1 homeobox DNA-binding domain.,
蛋白名称
Homeobox protein Hox-B1
其他名称
HOXB1; HOX2I; Homeobox protein Hox-B1; Homeobox protein Hox-2I; HOXA1; HOX1F; Homeobox protein Hox-A1; Homeobox protein Hox-1F; HOXD1; HOX4; HOX4G; Homeobox protein Hox-D1; Homeobox protein Hox-GG
Fields
>>Signaling pathways regulating pluripotency of stem cells
人蛋白质序列数据库
P14653/P49639/Q9GZZ0
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