免疫原
Synthesized peptide derived from human TRAP
特异性
The antibody can specifically recognize human TRAP protein.
来源
Mouse, Monoclonal/IgG1, Kappa
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.97% sodium azide.
稀释比例
IHC-p 1:100-500, IF 1:100-500
纯化工艺（Immunogen）
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
背景（Background）
This gene encodes an iron containing glycoprotein which catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is the most basic of the acid phosphatases and is the only form not inhibited by L(+)-tartrate. [provided by RefSeq, Aug 2008],
功能
catalytic activity:A phosphate monoester + H(2)O = an alcohol + phosphate.,cofactor:Binds 2 iron ions per subunit.,disease:This relatively minor intracellular isozyme of acid phosphatase can become the dominant isozyme in certain pathological states (Gaucher and Hodgkin diseases, the hairy cell, the B-cell, and the T-cell leukemias).,similarity:Belongs to the metallophosphoesterase superfamily. Purple acid phosphatase family.,subunit:Exists either as monomer or, after proteolytic processing, as a dimer of two chains linked by disulfide bond(s).,
其他名称
Tartrate-resistant acid phosphatase type 5 (TR-AP;EC 3.1.3.2;Tartrate-resistant acid ATPase;TrATPase;Type 5 acid phosphatase)
Fields
>>Riboflavin metabolism;>>Metabolic pathways;>>Lysosome;>>Osteoclast differentiation;>>Rheumatoid arthritis
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