免疫原
Synthesized peptide derived from human Factor XIIIa
特异性
This antibody detects endogenous levels of Factor XIIIa at Human
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
IHC-p 1:400. IF 1:50-200
纯化工艺（Immunogen）
The antibody was affinity-purified from Cell supernatant by affinity-chromatography using specific immunogen.
功能
catalytic activity:Protein glutamine + alkylamine = protein N(5)-alkylglutamine + NH(3).,cofactor:Binds 1 calcium ion per subunit.,disease:Defects in F13A1 are the cause of F13A deficiency [MIM:134570]. F13A deficiency is an autosomal recessive disorder characterized by a life-long bleeding tendency, impaired wound healing and spontaneous abortion in affected women. In addition to the common presentation such as subcutaneous and intramuscular haematomas, severe bleeding such as intracranial hemorrhages may occur.,function:Factor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyzes the formation of gamma-glutamyl-epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot. Also cross-link alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin.,online information:Factor XIII entry,online information:The Singapore human
基因名称（Gene Name）
F13A1 F13A
其他名称
Coagulation factor XIII A chain (Coagulation factor XIIIa;EC 2.3.2.13;Protein-glutamine gamma-glutamyltransferase A chain;Transglutaminase A chain)
Fields
>>Complement and coagulation cascades;>>Coronavirus disease - COVID-19
细胞定位
Cytoplasm. Secreted . Secreted into the blood plasma. Cytoplasmic in most tissues, but also secreted in the blood plasma.
组织表达
Brain,Pancreas,Plasma,
联系我们
关注我们
您当前的位置： 
说明书
成功添加到购物车
