免疫原
Synthesized peptide derived from human Cytokeratin 15 (CK15)
特异性
This antibody detects endogenous levels of Cytokeratin 15 (CK15) at Human
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
IHC-p 1:100. IF 1:50-200
纯化工艺(Immunogen)
The antibody was affinity-purified from Cell supernatant by affinity-chromatography using specific immunogen.
功能
miscellaneous:There are two types of cytoskeletal and microfibrillar keratin: I (acidic; 40-55 kDa) and II (neutral to basic; 56-70 kDa).,similarity:Belongs to the intermediate filament family.,subunit:Heterotetramer of two type I and two type II keratins.,tissue specificity:Expressed in a discontinuous manner in the basal cell layer of adult skin epidermis, but continuously in the basal layer of fetal skin epidermis and nail. Also expressed in the outer root sheath above the hair bulb in hair follicle (at protein level). Expressed homogeneously in all cell layers of the esophagus and exocervix, but detected in the basal cell layer only of oral mucosa, skin and in the basal plus the next two layers of the suprabasal epithelium of the palate.,
基因名称(Gene Name)
KRT15 KRTB
蛋白名称
Cytokeratin 15 (CK15)
其他名称
Keratin, type I cytoskeletal 15 (Cytokeratin-15;CK-15;Keratin-15;K15)
Fields
>>Estrogen signaling pathway;>>Staphylococcus aureus infection
细胞定位
nucleus,intermediate filament,extracellular exosome,
组织表达
Expressed in a discontinuous manner in the basal cell layer of adult skin epidermis, but continuously in the basal layer of fetal skin epidermis and nail. Also expressed in the outer root sheath above the hair bulb in hair follicle (at protein level). Expressed homogeneously in all cell layers of the esophagus and exocervix, but detected in the basal cell layer only of oral mucosa, skin and in the basal plus the next two layers of the suprabasal epithelium of the palate.