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GST-Pi (ABT256) Mouse mAb

说明书

BYab-15180

  • 20UL ¥460 50UL ¥945 100UL ¥1350
  • 货期: 3天左右

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宿主
反应性
应用
IHC;WB;
分子量(DA)
免疫原
Synthesized peptide derived from human GST-Pi
特异性
The antibody can specifically recognize human GST-Pi protein.
来源
Monoclonal Mouse IgG2b, Kappa
组成(Formulation)
PBS, pH7.2, 0.03% Porcolin 300, containing stabilizing protein
稀释比例
IHC-p 1:200-400, WB 1:200-1000,
纯化工艺(Immunogen)
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
浓度
背景(Background)
Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. This GST family member is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases. [provided by RefSeq, Jul 2008],
功能
catalytic activity:RX + glutathione = HX + R-S-glutathione.,function:Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.,online information:The Singapore human mutation and polymorphism database,similarity:Belongs to the GST superfamily. Pi family.,similarity:Contains 1 GST C-terminal domain.,similarity:Contains 1 GST N-terminal domain.,subunit:Homodimer.,
基因名称(Gene Name)
GSTP1 FAEES3 GST3
蛋白名称
Deafness;Deafness X-linked 7;DFN7;FAEES3;Fatty Acid Ethyl Ester Synthase III;Glutathione S Transferase 3;Glutathione S Transferase Pi;Glutathione S-transferase P;Glutathione S-transferase pi 1;GST cla
简称
GST-Pi
其他名称
Deafness;Deafness X-linked 7;DFN7;FAEES3;Fatty Acid Ethyl Ester Synthase III;Glutathione S Transferase 3;Glutathione S Transferase Pi;Glutathione S-transferase P;Glutathione S-transferase pi 1;GST class-pi;GST3;GSTP;Gstp1;GSTP1-1;GSTP1_HUMAN;PI;X linked 7
Fields
>>Glutathione metabolism;>>Metabolism of xenobiotics by cytochrome P450;>>Drug metabolism - cytochrome P450;>>Drug metabolism - other enzymes;>>Metabolic pathways;>>Platinum drug resistance;>>Pathways in cancer;>>Chemical carcinogenesis - DNA adducts;>>Prostate cancer;>>Hepatocellular carcinoma;>>Fluid shear stress and atherosclerosis
人基因ID
人蛋白质序列数据库
P09211
小鼠基因ID
小鼠蛋白质序列数据库
P19157
大鼠基因ID
大鼠蛋白质序列数据库
P04906
细胞定位
Cytoplasmic
组织表达
Esophageal squamous cell carcinoma
储存(Storage)
-20°C

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GST-Pi (ABT256) Mouse mAb

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