欢迎访问南京博研生物官网 服务热线:025-52298998 |
您当前的位置: 首页 > 产品中心 > 一抗 > 单克隆抗体

Cytokeratin 19&10 (ABT493) Mouse mAb

说明书

BYab-15153

  • 20UL ¥460 50UL ¥945 100UL ¥1350
  • 货期: 3天左右

产品简介 实验方案 引用文献 相关产品

产品简介>

宿主
反应性
应用
IHC,WB
分子量(DA)
免疫原
Synthesized peptide derived from human Cytokeratin 19&10
特异性
The antibody can recognize human CK10 and CK19 protein, and shows no cross reaction with CK1, 5, 6, 7, 8, 13, 14, 15, 17, 18, 20.
来源
Mouse, Monoclonal/IgG1, Kappa
组成(Formulation)
PBS, pH7.2, 0.03% Porcolin 300, containing stabilizing protein
稀释比例
IHC-p 1:200-400,WB: 500-1000
纯化工艺(Immunogen)
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
浓度
背景(Background)
The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21. [provided by RefSeq, Jul 2008],
功能
developmental stage:Present in hair follicles at all stages of development.,domain:This keratin differs from all other IF proteins in lacking the C-terminal tail domain.,function:Involved in the organization of myofibers. Together with KRT8, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle.,miscellaneous:There are two types of cytoskeletal and microfibrillar keratin: I (acidic; 40-55 kDa) and II (neutral to basic; 56-70 kDa).,similarity:Belongs to the intermediate filament family.,subunit:Heterotetramer of two type I and two type II keratins. Interacts with PNN and the actin-binding domain of DMD. Interacts with HCV core protein.,tissue specificity:Expressed in a defined zone of basal keratinocytes in the deep outer root sheath of hair follicles. Also observed in sweat gland and mammary gland ductal and secretory cells, bile ducts, gastrointestin
基因名称(Gene Name)
KRT19 KRT10
蛋白名称
Keratin, type I cytoskeletal 19/10 (Cytokeratin-19/10) (CK-19/10) (Keratin-19/10) (K19/10)
简称
Cytokeratin 19/10
其他名称
40 kDa keratin intermediate filament;CK 19;CK-19;CK19;Cytokeratin 19;Cytokeratin-19;K19;K1C19_HUMAN;K1CS;Keratin 19;Keratin type I 40 kD;Keratin type I 40kD;Keratin type I cytoskeletal 19;Keratin, type I cytoskeletal 19;Keratin, type I, 40 kd;Keratin-19;KRT19;MGC15366
Fields
>>Estrogen signaling pathway;>>Staphylococcus aureus infection
人基因ID
人蛋白质序列数据库
P08727/P13645
小鼠基因ID
小鼠蛋白质序列数据库
大鼠基因ID
大鼠蛋白质序列数据库
细胞定位
Cytoplasmic, Membranous
组织表达
Kindey/ Skin
储存(Storage)
-20°C

实验方案>

实验步骤

引用文献(0)>

相关产品>

成功添加到购物车

查看购物车 继续购物

Cytokeratin 19&10 (ABT493) Mouse mAb

筛选器: All

亮暗模式切换
X

在线
客服

在线客服
09:00 - 18:00

服务热线

服务
热线

客服服务热线

025-52298998
客服服务热线

扫码

扫码
咨询

微信二维码 微信扫一扫立即咨询
返回顶部 顶部