免疫原
The antiserum was produced against synthesized peptide derived from human SLK. AA range:1151-1200
特异性
SLK Polyclonal Antibody detects endogenous levels of SLK protein.
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Mediates apoptosis and actin stress fiber dissolution.,PTM:Autophosphorylated. Phosphorylated upon DNA damage, probably by ATM or ATR.,PTM:Proteolytically cleaved by caspase-3.,sequence caution:Contaminating sequence. Potential poly-A sequence starting in position 422.,sequence caution:Contaminating sequence. Potential poly-A sequence starting in position 611.,sequence caution:Contaminating sequence. Potential poly-A sequence starting in position 614.,similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 UVR domain.,tissue specificity:Ubiquitously expressed. Highest expression is found in heart and in skeletal muscle.,
功能
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Mediates apoptosis and actin stress fiber dissolution.,PTM:Autophosphorylated. Phosphorylated upon DNA damage, probably by ATM or ATR.,PTM:Proteolytically cleaved by caspase-3.,sequence caution:Contaminating sequence. Potential poly-A sequence starting in position 422.,sequence caution:Contaminating sequence. Potential poly-A sequence starting in position 611.,sequence caution:Contaminating sequence. Potential poly-A sequence starting in position 614.,similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 UVR domain.,tissue specificity:Ubiquitously expressed. Highest expression is found in heart and in skeletal muscle.,
蛋白名称
STE20-like serine/threonine-protein kinase
其他名称
SLK; KIAA0204; STK2; STE20-like serine/threonine-protein kinase; STE20-like kinase; hSLK; CTCL tumor antigen se20-9; STE20-related serine/threonine-protein kinase; STE20-related kinase; Serine/threonine-protein kinase 2
组织表达
Ubiquitously expressed. Highest expression is found in heart and in skeletal muscle.
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