免疫原
The antiserum was produced against synthesized peptide derived from human SGK269. AA range:111-160
特异性
SgK269 Polyclonal Antibody detects endogenous levels of SgK269 protein.
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB 1:500-2000;IHC-p 1:50-300
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
This gene encodes a non-receptor tyrosine kinase that is a member of the new kinase family three (NFK3) family. In migrating cells, the encoded protein is associated with the actin cytoskeleton and focal adhesions and promotes developing focal adhesion elongation. This protein may play a role in the regulation of cell migration, proliferation and cancer metastasis. [provided by RefSeq, Mar 2014],
功能
catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,similarity:Belongs to the protein kinase superfamily.,similarity:Contains 1 protein kinase domain.,
蛋白名称
Pseudopodium-enriched atypical kinase 1
其他名称
PEAK1; KIAA2002; Pseudopodium-enriched atypical kinase 1; Sugen kinase 269; Tyrosine-protein kinase SgK269
细胞定位
Cytoplasm, cytoskeleton . Cell junction, focal adhesion . Colocalizes with F-actin in serum-rich medium (PubMed:20534451). Actin colocalization is reduced during serum starvation (PubMed:20534451). .
组织表达
Brain,Epithelium,Lung,Mesangial cell,Smooth muscle,Spleen,
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