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PKAγ cat Polyclonal Antibody

说明书

BYab-14930

  • 20UL ¥460 50UL ¥945 100UL ¥1350
  • 货期: 3天左右

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宿主
反应性
应用
WB;IHC;IF;ELISA
分子量(DA)
40kD
免疫原
The antiserum was produced against synthesized peptide derived from human KAPCG. AA range:1-50
特异性
PKAγ cat Polyclonal Antibody detects endogenous levels of PKAγ cat protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/10000.. IF 1:50-200
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度
1 mg/ml
背景(Background)
Cyclic AMP-dependent protein kinase (PKA) consists of two catalytic subunits and a regulatory subunit dimer. This gene encodes the gamma form of its catalytic subunit. The gene is intronless and is thought to be a retrotransposon derived from the gene for the alpha form of the PKA catalytic subunit. [provided by RefSeq, Jul 2008],
功能
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,enzyme regulation:Activated by cAMP.,function:Phosphorylates a large number of substrates in the cytoplasm and the nucleus.,similarity:Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.,similarity:Contains 1 AGC-kinase C-terminal domain.,similarity:Contains 1 protein kinase domain.,subunit:A number of inactive tetrameric holoenzymes are produced by the combination of homo- or heterodimers of the different regulatory subunits associated with two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits.,tissue specificity:Testis specific. But important tissues such as brain and ovary have not been analyzed for the content of transcript.,
基因名称(Gene Name)
PRKACG
蛋白名称
cAMP-dependent protein kinase catalytic subunit gamma
简称
PKAγ cat
其他名称
PRKACG; cAMP-dependent protein kinase catalytic subunit gamma; PKA C-gamma
Fields
>>Endocrine resistance;>>MAPK signaling pathway;>>Ras signaling pathway;>>Calcium signaling pathway;>>cAMP signaling pathway;>>Chemokine signaling pathway;>>Oocyte meiosis;>>Autophagy - animal;>>Longevity regulating pathway;>>Longevity regulating pathway - multiple species;>>Adrenergic signaling in cardiomyocytes;>>Vascular smooth muscle contraction;>>Wnt signaling pathway;>>Hedgehog signaling pathway;>>Apelin signaling pathway;>>Tight junction;>>Gap junction;>>Platelet activation;>>Circadian entrainment;>>Thermogenesis;>>Long-term potentiation;>>Retrograde endocannabinoid signaling;>>Glutamatergic synapse;>>Cholinergic synapse;>>Serotonergic synapse;>>GABAergic synapse;>>Dopaminergic synapse;>>Olfactory transduction;>>Taste transduction;>>Inflammatory mediator regulation of TRP channels;>>Insulin signaling pathway;>>Insulin secretion;>>GnRH signaling pathway;>>Ovarian steroidogenesis;>>Progesterone-mediated oocyte maturation;>>Estrogen signaling pathway;>>Melanogenesis;>>Thyroid hormo
人基因ID
5568
人蛋白质序列数据库
P22612
小鼠基因ID
小鼠蛋白质序列数据库
大鼠基因ID
大鼠蛋白质序列数据库
细胞定位
nucleoplasm,cytosol,ciliary base,
组织表达
Testis specific. But important tissues such as brain and ovary have not been analyzed for the content of transcript.
储存(Storage)
-20°C/1 year

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PKAγ cat Polyclonal Antibody

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