免疫原
The antiserum was produced against synthesized peptide derived from human MOS. AA range:61-110
特异性
Mos Polyclonal Antibody detects endogenous levels of Mos protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
MOS is a serine/threonine kinase that activates the MAP kinase cascade through direct phosphorylation of the MAP kinase activator MEK (MAP2K1; MIM 176872) (Prasad et al., 2008 [PubMed 18246541]).[supplied by OMIM, Jul 2009],
功能
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,similarity:Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.,similarity:Contains 1 protein kinase domain.,tissue specificity:Expressed specifically in testis during spermatogenesis.,
蛋白名称
Proto-oncogene serine/threonine-protein kinase mos
其他名称
MOS; Proto-oncogene serine/threonine-protein kinase mos; Oocyte maturation factor mos; Proto-oncogene c-Mos
Fields
>>Oocyte meiosis;>>Regulation of actin cytoskeleton;>>Progesterone-mediated oocyte maturation
组织表达
Expressed specifically in testis during spermatogenesis.