免疫原
Synthesized peptide derived from Dyrk4 . at AA range: 350-430
特异性
Dyrk4 Polyclonal Antibody detects endogenous levels of Dyrk4 protein.
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
This gene encodes an enzyme that belongs to a conserved family of serine/threonine protein kinases. Members of this dual specificity kinase family are thought to function in the regulation of cell differentiation and proliferation, survival, and in development. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Aug 2013],
功能
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,function:Possible non-essential role in spermiogenesis.,PTM:Autophosphorylated on tyrosine residues.,similarity:Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.,similarity:Contains 1 protein kinase domain.,
蛋白名称
Dual specificity tyrosine-phosphorylation-regulated kinase 4
其他名称
DYRK4; Dual specificity tyrosine-phosphorylation-regulated kinase 4
细胞定位
[Isoform 1]: Cytoplasm .; [Isoform 4]: Cytoplasm . Nucleus .
组织表达
Brain,Kidney,Lung,Testis,
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