免疫原
The antiserum was produced against synthesized peptide derived from human AK5. AA range:391-440
特异性
AK5 Polyclonal Antibody detects endogenous levels of AK5 protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/5000.. IF 1:50-200
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
adenylate kinase 5(AK5) Homo sapiens This gene encodes a member of the adenylate kinase family, which is involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. This member is related to the UMP/CMP kinase of several species. It is located in the cytosol and expressed exclusively in brain. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008],
功能
catalytic activity:ATP + AMP = 2 ADP.,function:Active on AMP and dAMP with ATP as a donor. When GTP is used as phosphate donor, the enzyme phosphorylates AMP, CMP, and to a small extent dCMP.,similarity:Belongs to the adenylate kinase family.,subunit:Monomer.,tissue specificity:Brain specific.,
蛋白名称
Adenylate kinase isoenzyme 5
其他名称
AK5; Adenylate kinase isoenzyme 5; AK 5; ATP-AMP transphosphorylase 5
Fields
>>Purine metabolism;>>Thiamine metabolism;>>Metabolic pathways;>>Nucleotide metabolism;>>Biosynthesis of cofactors