免疫原
Synthesized phospho-peptide around the phosphorylation site of human Pragmin (phospho Tyr413)
特异性
Phospho-Pragmin (Y413) Polyclonal Antibody detects endogenous levels of Pragmin protein only when phosphorylated at Y413.
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/10000.. IF 1:50-200
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
This gene encodes an enzyme that belongs to the tyrosine protein kinase family. A similar protein in rat binds to Rho family GTPase 2 (Rnd2) and regulates neurite outgrowth via activation of Ras homolog gene family, member A (RhoA). [provided by RefSeq, Mar 2014],
功能
catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,similarity:Belongs to the protein kinase superfamily.,similarity:Contains 1 protein kinase domain.,
蛋白名称
Tyrosine-protein kinase SgK223
其他名称
SGK223; Tyrosine-protein kinase SgK223; Sugen kinase 223
细胞定位
Cytoplasm . Cell junction, focal adhesion . Nucleus . Colocalized with NOTCH1 in the nucleus. .
组织表达
Amygdala,Epithelium,Fetal brain,Spleen,
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