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CKMT2 mouse mAb

说明书

BYab-14228

  • 20UL ¥460 50UL ¥945 100UL ¥1350
  • 货期: 3天左右

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宿主
反应性
应用
WB
分子量(DA)
47kD
免疫原
Purified recombinant human CKMT2 protein fragments expressed in E.coli.
特异性
This antibody detects endogenous levels of CKMT2 and does not cross-react with related proteins.
来源
Monoclonal, Mouse
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
wb 1:1000
纯化工艺(Immunogen)
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
浓度
1 mg/ml
背景(Background)
creatine kinase, mitochondrial 2(CKMT2) Homo sapiens Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Sarcomeric mitochondrial creatine kinase has 80% homology with the coding exons of ubiquitous mitochondrial creatine kinase. This gene contains sequences homologous to several motifs that are shared among some nuclear genes encoding mitochondrial proteins and thus may be essential for the coordinated activation of these genes during mitochondrial biogenesis. Three transcript variants encoding the same protein have been found for this gen
功能
catalytic activity:ATP + creatine = ADP + phosphocreatine.,function:Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa.,miscellaneous:Mitochondrial creatine kinase binds cardiolipin.,similarity:Belongs to the ATP:guanido phosphotransferase family.,subunit:Exists as an octamer composed of four CKMT2 homodimers.,tissue specificity:Sarcomere-specific. Found only in heart and skeletal muscles.,
基因名称(Gene Name)
ckmt2
蛋白名称
简称
sMtCK
其他名称
CKMT 2;Basic-type mitochondrial creatine kinase;CKMT 2;CKMT2;CPK;Creatine kinase mitochondrial 2;Creatine kinase mitochondrial 2 (sarcomeric);Creatine kinase S-type; creatine kinase S-type, mitochondrial;KCRS_HUMAN;Mib CK;Mib-CK;mitochondrial; OTTHUMP00000147542;S-MtCK;Sarcomeric mitochondrial creatine kinase;SMTCK.
Fields
>>Arginine and proline metabolism;>>Metabolic pathways
人基因ID
1160
人蛋白质序列数据库
P17540
小鼠基因ID
小鼠蛋白质序列数据库
Q6P8J7
大鼠基因ID
大鼠蛋白质序列数据库
细胞定位
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
组织表达
Sarcomere-specific. Found only in heart and skeletal muscles.
储存(Storage)
-20°C/1 year

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CKMT2 mouse mAb

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