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Emt Monoclonal Antibody

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BYab-14135

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  • 货期: 3天左右

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宿主
反应性
应用
WB;IF;FCM;ELISA
分子量(DA)
免疫原
Purified recombinant fragment of human Emt expressed in E. Coli.
特异性
Emt Monoclonal Antibody detects endogenous levels of Emt protein.
来源
Monoclonal, Mouse
组成(Formulation)
Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.
稀释比例
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. Flow cytometry: 1/200 - 1/400. ELISA: 1/10000. Not yet tested in other applications.
纯化工艺(Immunogen)
Affinity purification
浓度
背景(Background)
This gene encodes an intracellular tyrosine kinase expressed in T-cells. The protein contains both SH2 and SH3 domains which are often found in intracellular kinases. It is thought to play a role in T-cell proliferation and differentiation. [provided by RefSeq, Jul 2008],
功能
catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,cofactor:Binds 1 zinc ion per subunit.,function:Plays a role in T-cell proliferation and differentiation.,induction:By interleukin-2.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. TEC subfamily.,similarity:Contains 1 Btk-type zinc finger.,similarity:Contains 1 PH domain.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 SH2 domain.,similarity:Contains 1 SH3 domain.,subcellular location:Localizes to cell surface receptors in the plasma membrane after stimulation with respective receptors (TCR, CD28, CD2) in T-cells.,tissue specificity:T-cell lines and natural killer cell lines.,
基因名称(Gene Name)
ITK
蛋白名称
Tyrosine-protein kinase ITK/TSK
简称
Emt
其他名称
ITK; EMT; LYK; Tyrosine-protein kinase ITK/TSK; Interleukin-2-inducible T-cell kinase; IL-2-inducible T-cell kinase; Kinase EMT; T-cell-specific kinase; Tyrosine-protein kinase Lyk
Fields
>>Chemokine signaling pathway;>>T cell receptor signaling pathway;>>Leukocyte transendothelial migration
人基因ID
3702
人蛋白质序列数据库
Q08881
小鼠基因ID
小鼠蛋白质序列数据库
Q03526
大鼠基因ID
大鼠蛋白质序列数据库
细胞定位
Cytoplasm . Nucleus . Localizes in the vicinity of cell surface receptors in the plasma membrane after receptor stimulation.
组织表达
T-cell lines and natural killer cell lines.
储存(Storage)
-20°C/1 year

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Emt Monoclonal Antibody

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