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CD53 Polyclonal Antibody

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BYab-14056

  • 20UL ¥460 50UL ¥945 100UL ¥1350
  • 货期: 3天左右

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宿主
反应性
应用
WB;ELISA
分子量(DA)
24kD
免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human CD53. AA range:91-140
特异性
CD53 Polyclonal Antibody detects endogenous levels of CD53 protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度
1 mg/ml
背景(Background)
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. It contributes to the transduction of CD2-generated signals in T cells and natural killer cells and has been suggested to play a role in growth regulation. Familial deficiency of this gene has been linked to an immunodeficiency associated with recurrent infectious diseases caused by bacteria, fungi and viruses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016],
功能
function:May be involved in growth regulation in hematopoietic cells.,similarity:Belongs to the tetraspanin (TM4SF) family.,tissue specificity:B-cells, monocytes, macrophages, neutrophils, single (CD4 or CD8) positive thymocytes and peripheral T-cells.,
基因名称(Gene Name)
CD53
蛋白名称
Leukocyte surface antigen CD53
简称
CD53
其他名称
CD53; MOX44; TSPAN25; Leukocyte surface antigen CD53; Cell surface glycoprotein CD53; Tetraspanin-25; Tspan-25; CD53
Fields
人基因ID
963
人蛋白质序列数据库
P19397
小鼠基因ID
12508
小鼠蛋白质序列数据库
Q61451
大鼠基因ID
24251
大鼠蛋白质序列数据库
P24485
细胞定位
Cell membrane . Cell junction . Membrane; Multi-pass membrane protein. Concentrates in localized microdomains along the plasma membrane at the contact sites between cells of fused myotubes. .
组织表达
B-cells, monocytes, macrophages, neutrophils, single (CD4 or CD8) positive thymocytes and peripheral T-cells.
储存(Storage)
-20°C/1 year

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CD53 Polyclonal Antibody

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