免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human CD200. AA range:171-220
特异性
CD200 Polyclonal Antibody detects endogenous levels of CD200 protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000.. IF 1:50-200
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
This gene encodes a type I membrane glycoprotein containing two extracellular immunoglobulin domains, a transmembrane and a cytoplasmic domain. This gene is expressed by various cell types, including B cells, a subset of T cells, thymocytes, endothelial cells, and neurons. The encoded protein plays an important role in immunosuppression and regulation of anti-tumor activity. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016],
功能
function:Costimulates T-cell proliferation. May regulate myeloid cell activity in a variety of tissues.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,subunit:Interacts with CD200R1.,
蛋白名称
OX-2 membrane glycoprotein
其他名称
CD200; MOX1; MOX2; My033; OX-2 membrane glycoprotein; CD200
细胞定位
Cell membrane; Single-pass type I membrane protein.
组织表达
Blood,Brain,Fetal brain,