免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human CD37. AA range:81-130
特异性
CD37 Polyclonal Antibody detects endogenous levels of CD37 protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000.. IF 1:50-200
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It may play a role in T-cell-B-cell interactions. Alternate splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],
功能
similarity:Belongs to the tetraspanin (TM4SF) family.,tissue specificity:B-lymphocytes.,
蛋白名称
Leukocyte antigen CD37
其他名称
CD37; TSPAN26; Leukocyte antigen CD37; Tetraspanin-26; Tspan-26; CD37
Fields
>>Hematopoietic cell lineage
细胞定位
Membrane; Multi-pass membrane protein.