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CD207 Polyclonal Antibody

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BYab-14005

  • 20UL ¥460 50UL ¥945 100UL ¥1350
  • 货期: 3天左右

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宿主
反应性
应用
WB;ELISA
分子量(DA)
38kD
免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human CD207. AA range:61-110
特异性
CD207 Polyclonal Antibody detects endogenous levels of CD207 protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度
1 mg/ml
背景(Background)
The protein encoded by this gene is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. Mutations in this gene result in Birbeck granules deficiency or loss of sugar binding activity. [provided by RefSeq, Aug 2010],
功能
function:Calcium-dependent lectin displaying mannose-binding specificity, Induces the formation of Birbeck granules (BGs); is a potent regulator of membrane superimposition and zippering.,online information:Langerin,similarity:Contains 1 C-type lectin domain.,subcellular location:Found in Birbeck granules (BGs), which are organelles consisting of superimposed and zippered membranes.,tissue specificity:Exclusively expressed by Langerhans cells.,
基因名称(Gene Name)
CD207
蛋白名称
C-type lectin domain family 4 member K
简称
CD207
其他名称
CD207; CLEC4K; C-type lectin domain family 4 member K; Langerin; CD207
Fields
人基因ID
50489
人蛋白质序列数据库
Q9UJ71
小鼠基因ID
246278
小鼠蛋白质序列数据库
Q8VBX4
大鼠基因ID
大鼠蛋白质序列数据库
细胞定位
Membrane ; Single-pass type II membrane protein . Found in Birbeck granules (BGs), which are organelles consisting of superimposed and zippered membranes.
组织表达
Exclusively expressed by Langerhans cells. Expressed in astrocytoma and malignant ependymoma, but not in normal brain tissues.
储存(Storage)
-20°C/1 year

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CD207 Polyclonal Antibody

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