免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human CD58. AA range:31-80
特异性
CD58 Polyclonal Antibody detects endogenous levels of CD58 protein.
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000.. IF 1:50-200
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
This gene encodes a member of the immunoglobulin superfamily. The encoded protein is a ligand of the T lymphocyte CD2 protein, and functions in adhesion and activation of T lymphocytes. The protein is localized to the plasma membrane. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2009],
功能
function:Ligand of the T-lymphocyte CD2 glycoprotein. This interaction is important in mediating thymocyte interactions with thymic epithelial cells, antigen-independent and -dependent interactions of T-lymphocytes with target cells and antigen-presenting cells and the T-lymphocyte rosetting with erythrocytes. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,
蛋白名称
Lymphocyte function-associated antigen 3
其他名称
CD58; LFA3; Lymphocyte function-associated antigen 3; Ag3; Surface glycoprotein LFA-3; CD58
Fields
>>Cell adhesion molecules;>>Epstein-Barr virus infection
细胞定位
[Isoform 1]: Cell membrane; Single-pass type I membrane protein.
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