免疫原
The antiserum was produced against synthesized peptide derived from human LILRA1. AA range:53-102
特异性
LIR-6 Polyclonal Antibody detects endogenous levels of LIR-6 protein.
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB 1:500-2000;IHC-p 1:50-300
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
This gene encodes an activating member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein is predominantly expressed in B cells, interacts with major histocompatibility complex class I ligands, and contributes to the regulation of immune responses. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013],
功能
function:May act as receptor for class I MHC antigens.,similarity:Contains 4 Ig-like C2-type (immunoglobulin-like) domains.,tissue specificity:Detected in monocytes and B-cells.,
蛋白名称
Leukocyte immunoglobulin-like receptor subfamily A member 1
其他名称
LILRA1; LIR6; Leukocyte immunoglobulin-like receptor subfamily A member 1; CD85 antigen-like family member I; Leukocyte immunoglobulin-like receptor 6; LIR-6; CD antigen CD85i
Fields
>>Osteoclast differentiation;>>B cell receptor signaling pathway
细胞定位
Membrane; Single-pass type I membrane protein.
组织表达
Detected in monocytes and B-cells.
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