免疫原
The antiserum was produced against synthesized peptide derived from human EMR4P. AA range:101-150
特异性
EMR4 Polyclonal Antibody detects endogenous levels of EMR4 protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
This gene is a member of the EGF-TM7 receptor gene family which is thought to play a role in leukocyte adhesion and migration. In other vertebrates, including nonhuman primates, this gene encodes a protein containing N-terminal EGF domains and a C-terminal transmembrane domain. Sequence evidence for the human gene, however, indicates nucleotide deletion in the genomic sequence would result in frameshift and early termination of translation. A protein expressed by this gene would be soluble rather than expressed on the cell surface. As the encoded protein has not been detected, this gene may represent a transcribed pseudogene. [provided by RefSeq, Aug 2008],
蛋白名称
Putative EGF-like module-containing mucin-like hormone receptor-like 4
其他名称
EMR4P; EMR4; GPR127; PGR16; Putative EGF-like module-containing mucin-like hormone receptor-like 4; EGF-like module receptor 4; G-protein coupled receptor 127; G-protein coupled receptor PGR16
细胞定位
[Isoform 1]: Cell membrane ; Multi-pass membrane protein .; [Isoform 2]: Secreted .