欢迎访问南京博研生物官网 服务热线:025-52298998 |
您当前的位置: 首页 > 产品中心 > 一抗 > 多克隆抗体

GPR56 Polyclonal Antibody

说明书

BYab-13344

  • 20UL ¥460 50UL ¥945 100UL ¥1350
  • 货期: 3天左右

产品简介 实验方案 引用文献 相关产品

产品简介>

宿主
反应性
应用
WB;IF;ELISA
分子量(DA)
78kD
免疫原
The antiserum was produced against synthesized peptide derived from human GPR56. AA range:251-300
特异性
GPR56 Polyclonal Antibody detects endogenous levels of GPR56 protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度
1 mg/ml
背景(Background)
This gene encodes a member of the G protein-coupled receptor family and regulates brain cortical patterning. The encoded protein binds specifically to transglutaminase 2, a component of tissue and tumor stroma implicated as an inhibitor of tumor progression. Mutations in this gene are associated with a brain malformation known as bilateral frontoparietal polymicrogyria. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014],
功能
disease:Defects in GPR56 are the cause of bilateral frontoparietal polymicrogyria (BFPP) [MIM:606854]. BFPP is characterized by disorganized cortical lamination that is most severe in frontal cortex.,function:Could be involved in cell-cell interactions.,similarity:Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.,similarity:Contains 1 GPS domain.,tissue specificity:Widely distributed with highest levels found in thyroid gland, brain and heart. Expressed in a great number of tumor cells.,
基因名称(Gene Name)
GPR56
蛋白名称
G-protein coupled receptor 56
简称
GPR56
其他名称
GPR56; TM7LN4; TM7XN1; G-protein coupled receptor 56; Protein TM7XN1
Fields
人基因ID
9289
人蛋白质序列数据库
Q9Y653
小鼠基因ID
小鼠蛋白质序列数据库
Q8K209
大鼠基因ID
大鼠蛋白质序列数据库
细胞定位
Cell membrane ; Multi-pass membrane protein .; [ADGRG1 N-terminal fragment]: Secreted .; [ADGRG1 C-terminal fragment]: Membrane raft . Interaction with its ligand COL3A1 leads to the release of ADGRG1 NT from the membrane and triggers the association of ADGRG1 CT with lipid rafts. .
组织表达
Widely distributed with highest levels found in thyroid gland, brain and heart. Expressed in a great number of tumor cells. Expression is down-regulated in different tumors from highly metastatic cells.
储存(Storage)
-20°C/1 year

实验方案>

实验步骤

引用文献(0)>

相关产品>

成功添加到购物车

查看购物车 继续购物

GPR56 Polyclonal Antibody

筛选器: All

亮暗模式切换
X

在线
客服

在线客服
09:00 - 18:00

服务热线

服务
热线

客服服务热线

025-52298998
客服服务热线

扫码

扫码
咨询

微信二维码 微信扫一扫立即咨询
返回顶部 顶部