免疫原
The antiserum was produced against synthesized peptide derived from human GPR133. AA range:461-510
特异性
GPR133 Polyclonal Antibody detects endogenous levels of GPR133 protein.
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
The adhesion G-protein-coupled receptors (GPCRs), including GPR133, are membrane-bound proteins with long N termini containing multiple domains. GPCRs, or GPRs, contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins (summary by Bjarnadottir et al., 2004 [PubMed 15203201]).[supplied by OMIM, Nov 2010],
功能
function:Orphan receptor.,similarity:Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.,similarity:Contains 1 GPS domain.,
蛋白名称
Probable G-protein coupled receptor 133
其他名称
GPR133; PGR25; Probable G-protein coupled receptor 133; G-protein coupled receptor PGR25
细胞定位
Cell membrane ; Multi-pass membrane protein .
组织表达
Up-regulated in CD133(+) cell population of glioblastoma.
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