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FRP-2 Polyclonal Antibody

说明书

BYab-13264

  • 20UL ¥460 50UL ¥945 100UL ¥1350
  • 货期: 3天左右

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宿主
反应性
应用
WB;ELISA
分子量(DA)
30kD
免疫原
The antiserum was produced against synthesized peptide derived from human SFRP2. AA range:119-168
特异性
FRP-2 Polyclonal Antibody detects endogenous levels of FRP-2 protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度
1 mg/ml
背景(Background)
This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. Methylation of this gene is a potential marker for the presence of colorectal cancer. [provided by RefSeq, Jul 2008],
功能
domain:The FZ domain is involved in binding with Wnt ligands.,function:Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP2 may be important for eye retinal development and for myogenesis.,similarity:Belongs to the secreted frizzled-related protein (sFRP) family.,similarity:Contains 1 FZ (frizzled) domain.,similarity:Contains 1 NTR domain.,tissue specificity:Expressed in adipose tissue, heart, brain, skeletal muscle, pancreas, thymus, prostate, testis, ovary, small intestine and colon. Highest levels in adipose tissue, small intestine and colon.,
基因名称(Gene Name)
SFRP2
蛋白名称
Secreted frizzled-related protein 2
简称
FRP-2
其他名称
SFRP2; FRP2; SARP1; FKSG12; Secreted frizzled-related protein 2; FRP-2; sFRP-2; Secreted apoptosis-related protein 1; SARP-1
Fields
>>Wnt signaling pathway
人基因ID
6423
人蛋白质序列数据库
Q96HF1
小鼠基因ID
20319
小鼠蛋白质序列数据库
P97299
大鼠基因ID
大鼠蛋白质序列数据库
细胞定位
Secreted .
组织表达
Expressed in adipose tissue, heart, brain, skeletal muscle, pancreas, thymus, prostate, testis, ovary, small intestine and colon. Highest levels in adipose tissue, small intestine and colon.
储存(Storage)
-20°C/1 year

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FRP-2 Polyclonal Antibody

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