免疫原
The antiserum was produced against synthesized peptide derived from human BRS3. AA range:161-210
特异性
BRS-3 Polyclonal Antibody detects endogenous levels of BRS-3 protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
The protein encoded by this gene is a G protein-coupled membrane receptor that binds bombesin-like peptides. This binding results in activation of a phosphatidylinositol-calcium second messenger system, with physiological effects including regulation of metabolic rate, glucose metabolism, and hypertension. [provided by RefSeq, Sep 2011],
功能
function:Role in sperm cell division, maturation, or function. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:In germ cells in testis. Lung carcinoma cells.,
蛋白名称
Bombesin receptor subtype-3
其他名称
BRS3; Bombesin receptor subtype-3; BRS-3
Fields
>>Neuroactive ligand-receptor interaction
细胞定位
Cell membrane; Multi-pass membrane protein.
组织表达
In germ cells in testis. Lung carcinoma cells.