免疫原
Synthesized peptide derived from human EPHB3 (Phospho Tyr608)
特异性
This antibody detects endogenous levels of Human,Mouse,Rat EPHB3 (Phospho Tyr608)
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB 1:1000-2000 ELISA 1:5000-20000
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景（Background）
Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into two groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. This gene encodes a receptor for ephrin-B family members. [provided by RefSeq, Mar 2010],
功能
catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,function:Receptor for members of the ephrin-B family. Binds to ephrin-B1 and -B2.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 SAM (sterile alpha motif) domain.,similarity:Contains 2 fibronectin type-III domains.,tissue specificity:Ubiquitous.,
基因名称（Gene Name）
EPHB3 ETK2 HEK2 TYRO6
蛋白名称
EPHB3 (Phospho Tyr608)
其他名称
Ephrin type-B receptor 3 (EC 2.7.10.1;EPH-like tyrosine kinase 2;EPH-like kinase 2;Embryonic kinase 2;EK2;hEK2;Tyrosine-protein kinase TYRO6)
细胞定位
Cell membrane ; Single-pass type I membrane protein . Cell projection, dendrite .
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