免疫原
Synthesized peptide derived from GABA T-3 . at AA range: 370-450
特异性
GABA T-3 Polyclonal Antibody detects endogenous levels of GABA T-3 protein.
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
The protein encoded by this gene is a sodium-dependent transporter that uptakes gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter, which ends the GABA neurotransmission. Defects in this gene may result in epilepsy, behavioral problems, or intellectual problems. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015],
功能
function:Terminates the action of GABA by its high affinity sodium-dependent reuptake into presynaptic terminals.,similarity:Belongs to the sodium:neurotransmitter symporter (SNF) family.,tissue specificity:Widespread distribution in the brain.,
蛋白名称
Sodium- and chloride-dependent GABA transporter 3
其他名称
SLC6A11; GABT3; GAT3; Sodium- and chloride-dependent GABA transporter 3; GAT-3; Solute carrier family 6 member 11
Fields
>>Synaptic vesicle cycle;>>GABAergic synapse
细胞定位
Membrane; Multi-pass membrane protein.
组织表达
Widespread distribution in the brain.
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