免疫原
The antiserum was produced against synthesized peptide derived from human ALS2CR4. AA range:181-230
特异性
ALS2CR4 Polyclonal Antibody detects endogenous levels of ALS2CR4 protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
The protein encoded by this gene is a tetraspanin protein that is thought to be involved in WNT signaling. Defects in this gene are a cause of Joubert syndrome-14. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012],
蛋白名称
Transmembrane protein 237
其他名称
TMEM237; ALS2CR4; Transmembrane protein 237; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 4 protein
细胞定位
Membrane ; Multi-pass membrane protein . Cell projection, cilium . Localizes at the proximal region of primary cilia were observed, consistent with localization to the transition zone. Anchored to the transition zone by RPGRIP1L.
组织表达
Brain,Fetal skin,Ovary,