免疫原
Synthesized peptide derived from human FGF-19
特异性
This antibody detects endogenous levels of Human FGF-19
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB 1:1000-2000 ELISA 1:5000-20000
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景（Background）
function:May be involved in brain development during embryogenesis.,miscellaneous:Contrarily to other members of the family that can bind several FGF receptors FGF19 is specific for FGFR4.,similarity:Belongs to the heparin-binding growth factors family.,tissue specificity:Expressed in fetal brain, cartilage, retina, and adult gall bladder.,
功能
ameboidal cell migration, neural crest cell migration, cell motion, heart development, negative regulation of biosynthetic process, positive regulation of signal transduction, regulation of cellular ketone metabolic process,regulation of protein kinase cascade, positive regulation of cell communication, positive regulation of protein kinase cascade, regulation of glucose transport, positive regulation of glucose transport, negative regulation of steroid biosynthetic process, mesenchymal cell development, neural crest cell development, neural crest cell differentiation,cell migration, regulation of lipid metabolic process, regulation of steroid metabolic process, negative regulation of cellular biosynthetic process, regulation of MAPKKK cascade, positive regulation of MAPKKK cascade, negative regulation of lipid metabolic process, negative regulation of steroid metabolic process, regulati
基因名称（Gene Name）
FGF19 UNQ334/PRO533
其他名称
Fibroblast growth factor 19 (FGF-19)
Fields
>>MAPK signaling pathway;>>Ras signaling pathway;>>Rap1 signaling pathway;>>Calcium signaling pathway;>>PI3K-Akt signaling pathway;>>Regulation of actin cytoskeleton;>>Pathways in cancer;>>Melanoma;>>Breast cancer;>>Gastric cancer
组织表达
Expressed in fetal brain, cartilage, retina, and adult gall bladder.
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