免疫原
Synthesized peptide derived from human CSAD AA range: 195-245
特异性
This antibody detects endogenous levels of CSAD at Human/Mouse/Rat
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景（Background）
This gene encodes a member of the group 2 decarboxylase family. A similar protein in rodents plays a role in multiple biological processes as the rate-limiting enzyme in taurine biosynthesis, catalyzing the decarboxylation of cysteinesulfinate to hypotaurine. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011],
功能
catalytic activity:3-sulfino-L-alanine = hypotaurine + CO(2).,cofactor:Pyridoxal phosphate.,pathway:Organosulfur biosynthesis; taurine biosynthesis; hypotaurine from L-cysteine: step 2/2.,similarity:Belongs to the group II decarboxylase family.,subunit:Homodimer.,
Fields
>>beta-Alanine metabolism;>>Taurine and hypotaurine metabolism;>>Pantothenate and CoA biosynthesis;>>Metabolic pathways
组织表达
Expressed in liver and brain. Also expressed in both astrocytes and neurons, but lower levels are expressed in astrocytes.
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