免疫原
Synthesized peptide derived from human PRD14 AA range: 391-441
特异性
This antibody detects endogenous levels of PRD14 at Human/Mouse
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB 1:500-2000;IHC-p 1:50-300
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景(Background)
This gene encodes a member of the PRDI-BF1 and RIZ homology domain containing (PRDM) family of transcriptional regulators. The encoded protein may possess histone methyltransferase activity and plays a critical role in cell pluripotency by suppressing the expression of differentiation marker genes. Expression of this gene may play a role in breast cancer. [provided by RefSeq, Dec 2011],
功能
function:May be involved in transcriptional regulation.,similarity:Contains 1 SET domain.,similarity:Contains 6 C2H2-type zinc fingers.,
组织表达
Expressed in embryonic stem cells. Tends to be overexpressed in breast cancer (at protein level).